Early detection of Bevacizumb and Sunitinib mediated cardiotoxicity
نویسندگان
چکیده
The Utility of Cardiac Biomarkers and Echocardiography for the 3 Early Detection of Bevacizumab and Sunitinib Mediated Cardiotoxicity 4 5 Kimberly-Ann Bordun, Sheena Premecz, Megan daSilva, Soma Mandal, Vineet Goyal, 6 Tamara Glavinovic, Matthew Cheung,David Cheung, Christopher W. White, 7 Rakesh Chaudhary, Darren H. Freed, Hector R. Villarraga, Joerg Herrmann, 8 Manish Kohli, Amir Ravandi, James Thliveris, Marshall Pitz, Pawan K. Singal, 9 Sharon Mulvagh, Davinder S. Jassal 10 11
منابع مشابه
The utility of cardiac biomarkers and echocardiography for the early detection of bevacizumab- and sunitinib-mediated cardiotoxicity.
The recent introduction of novel anticancer therapies, including bevacizumab (BVZ) and sunitinib (SNT), is associated with an increased risk of cardiotoxicity. However, early identification of left ventricular (LV) systolic dysfunction may facilitate dose modification and avoid the development of advanced heart failure. Using a murine model of BVZ- and SNT-mediated cardiotoxicity, we investigat...
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